Maintenance of Vacuum System in Freeze Drying
Freeze dryer (freeze dryer) consists of refrigeration system, vacuum system, heating system and electrical instrument control system. The main components are drying box, condenser, refrigeration unit, vacuum pump, heating/cooling device, etc. In the 21st century, vacuum freeze-drying technology has attracted more and more attention because of its incomparable advantages compared with other drying methods. In addition to its wide application in the fields of medicine, biological products, food, blood products and active substances, its application scale and field are expanding.
The vacuum system is mainly composed of vacuum pump, front box, back box, valve on box body, mushroom valve, small butterfly valve, vacuum silicon tube and so on.
1. Regular replacement of vacuum pump oil to ensure the performance of the vacuum pump.
The performance of the vacuum pump decreases and the vacuum pump oil is polluted. If it is found that oil level drops and oil emulsifies, the quantity of oil should be increased or the vacuum pump oil should be replaced immediately, and the cause of pollution should be ascertained. If the vacuum pump sucks a small amount of water, the air ballast valve can be opened for 0.5-1 h to observe whether the appearance of the vacuum pump oil is improved and whether the vacuum degree continues to decrease. If the vacuum pump oil is replaced many times, the vacuum pump oil is obviously improved. The vacuum pump needs to be repaired.
2. Before starting the vacuum pump, check whether the oil level is normal (about 1/2 of the oil mirror position).
3. Make sure that the back chamber is dry before vacuum pumping. Avoid pumping water vapor into the pump body and affect the pumping efficiency of the vacuum pump.
The air tightness of the system decreases and leaks occur. Find the leak point, after finding the leak point, repair the leak, replace the sealing ring or replace the valve.
Vacuum freeze-drying industry in the drying subdivision industry has made great progress in the past decade. Life science research: antibody, protein, tissue, microbial research, so vacuum freeze-drying has been widely used in the field of biopharmaceuticals. Vacuum freeze-drying is widely used in pharmaceutical industry to prepare vaccines and antibiotics. In the field of health products, a large number of freeze-dried health products have been active in the health products market, such as freeze-dried cordyceps, freeze-dried sea cucumbers, freeze-dried antler, freeze-dried Dendrobium and so on.
Roots vacuum pump
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